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ForwardElastic Fibers Of The Internal Elastic Lamina Are Unraveled But Not Created With Expanding Arterial Diameter In Arteriogenesis
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.
Knowledge Strategy
With a better understanding of the mechanisms governing arteriogenesis, we may find pharmacological targets that could enhance collateral artery formation. This could lead to a pharmacological therapy that effectively increases blood flow to an ischemic tissue which would revolutionize management of patients with arterial occlusive diseases.
Professional Practice Gap
Patients suffering from arterial occlusive diseases would benefit tremendously if there were an effective medical therapy that could revascularize ischemic tissues. Collateral arteries develop (in a process termed arteriogenesis) as a spontaneous adaptation when a large conductance artery becomes occluded. The importance of collateral arteries for maintaining organ and limb perfusion has long been recognized, but their development is incompletely understood. If enhanced collateral artery development could be achieved thorough pharmacological means, it would offer a promising means to noninvasively enhance perfusion for these patients.
Learning Objectives
To create a virtual environment for the exchange of basic and translational vascular science that stimulates thoughtful discussion and motivates participants to discover solutions to important problems affecting vascular patients.
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The opinions or views expressed on the SVS OnDemand platform and the SVS Video Library are those of the faculty and do not necessarily reflect the opinions, recommendations, or endorsement of SVS. Participants should critically appraise the information presented and are encouraged to consult appropriate resources for information surrounding any product or device mentioned. Information presented, as well as publications, technologies, products and/or services discussed, are intended to inform the learner about the knowledge, techniques, and experiences of SVS faculty who are willing to share such information with colleagues. The SVS disclaims any and all liability for damages to any individual user for all claims which may result from the use of said information, publications, technologies, products and/or services and events.
Price
This content is provided to members of the Society for Vascular Surgery as a member benefit. If you are not a current member of SVS click here for information on how to apply for membership.