Title
Category
Credits
Event date
Cost
Elastic Fibers Of The Internal Elastic Lamina Are Unraveled But Not Created With Expanding Arterial Diameter In Arteriogenesis
  • Acute Upper Extremity Ischemia
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyWith a better understanding of the mechanisms governing arteriogenesis, we may find pharmacological targets that could enhance collateral artery formation. This could lead to a pharmacological therapy that effectively increases blood flow to an ischemic tissue which would revolutionize management of patients with arterial occlusive diseases.
Programmed Death Ligand-1 Regulates T-cells And M2 Macrophages to Control Wall Thickening During Arteriovenous Fistula Maturation
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyPDL1 antibody increased T-helper cells and decreased Treg, consistent with increase of inflammation. Moreover, PDL1 antibody reduced vascular wall thickening during AVF maturation. These results indicate that PDL1 have a critical role to cause inflammation during AVF maturation and might be a therapeutic target to improve AVF success.
TRPC6 Depletion Results in Loss of Myocardin And Phenotypic Modulation In Vascular Smooth Muscle Cells
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyThis research describes a novel, TRPC6-dependent pathway that regulates vascular smooth muscle cells phenotype. The results of this study may lead to mechanism-based therapies to reduce phenotypic switching, and thus mitigate neointimal hyperplasia, following vascular intervention.
Absence Of Cpla2 In Lrp1 Smooth Muscle Cell Deficient Mice Promotes Severe Aortic Atherosclerotic Disease
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System Knowledge StrategyResults from our studies will identify molecular mechanisms in the process of underpinning novel therapeutic targets for the devastating consequences of treating atherosclerotic disease plaque vulnerability and rupture by studying bioactive lipid dysregulation.
ZEB2 Regulates Activation And Exhaustion Programming Of CD8+ T Cells In Atherosclerosis
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System. 
The Role Of Mast Cells In Atherosclerotic Plaque Calcification
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System.Knowledge StrategyMast cell phenotype and secreting mediators could be detected in the plasma of patients with carotid atherosclerotic plaque and predict the clinical outcome of the patient.