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  • Basic and Translational Research
  • Translational Science Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge Strategy Develop new diagnostic and treatment modalities for AAAProfessional Practice Gap Experimental AAA models are subacute.
  • Basic and Translational Research
  • Translational Science Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices.Knowledge StrategyThis study demonstrated that BTK inhibitor ibrutinib, FDA-approved drug, attenuated the formation of, and further progression of established, experimental AAAs in two mechanistically distinct but complementary AAA model systems. Our results suggest that pharmacological inhibition of BTK may represent a novel translational strategy for AAA disease suppression.