Title
Category
Credits
Event date
Cost
  • Acute Limb Ischemia
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyWith a better understanding of the mechanisms governing arteriogenesis, we may find pharmacological targets that could enhance collateral artery formation. This could lead to a pharmacological therapy that effectively increases blood flow to an ischemic tissue which would revolutionize management of patients with arterial occlusive diseases.
  • Basic and Translational Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyThis research is demonstrating the efficacy of a novel compound that may help to reduce neointimal hyperplasia following vascular intervention.Professional Practice GapThe analogue discussed in this abstract may provide durable patency following vascular interventions. 
  • Basic and Translational Research
  • Neo Intimal Hyperplasia
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyThe results of this project, and subsequent projects it leads to, can lead to a paradigm shifting technology that can completely alter how we treat vascular diseases, improving outcomes and the overall cost of cardiovascular disease.
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyPDL1 antibody increased T-helper cells and decreased Treg, consistent with increase of inflammation. Moreover, PDL1 antibody reduced vascular wall thickening during AVF maturation. These results indicate that PDL1 have a critical role to cause inflammation during AVF maturation and might be a therapeutic target to improve AVF success.
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease.Knowledge StrategyThis research describes a novel, TRPC6-dependent pathway that regulates vascular smooth muscle cells phenotype. The results of this study may lead to mechanism-based therapies to reduce phenotypic switching, and thus mitigate neointimal hyperplasia, following vascular intervention.
  • Basic and Translational Research
  • Neo Intimal Hyperplasia
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease. Knowledge StrategyPeriadventitial delivery of simvastatin from microparticles attenuates arteriovenous fistula outflow vein neointimal hyperplasia. It provides a new option to prevent arteriovenous fistula failure.Professional Practice GapIn the present study, there was no assembled marker on simvastatin or microparticles, which could illustrate migration or residual dose in the outflow veins. 
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System Knowledge StrategyResults from our studies will identify molecular mechanisms in the process of underpinning novel therapeutic targets for the devastating consequences of treating atherosclerotic disease plaque vulnerability and rupture by studying bioactive lipid dysregulation.
  • Basic and Translational Research
  • Extremity Ischemia
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System.Knowledge StrategyThis study showed that circulating fatty acid synthase (cFAS) is independently associated with CLTI but not DM. Future studies may explore using cFAS as biomarker for severity of PAD to guide clinical management, or as a target for development of medical therapeutics.
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System. 
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System.Knowledge StrategyMast cell phenotype and secreting mediators could be detected in the plasma of patients with carotid atherosclerotic plaque and predict the clinical outcome of the patient.

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