Title
Category
Credits
Event date
Cost
Polygenic Risk Score Identifies Patients At Increased Risk For Abdominal Aortic Aneurysm And May Benefit From Ultrasound Screening
  • Basic and Translational Research
  • Aortic Aneurysm Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System. Knowledge StrategyThrough the use of low cost genotyping, we are able to identify a subset of the population at higher risk for AAA and who may benefit from screening beyond the current USPSTF recommendations.
Epigenetic Modifications Influence Macrophage-mediated Inflammation Inabdominal Aortic Aneurysms
  • Basic and Translational Research
  • Epigenetics in Vascular Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge Strategy The results of this study allow us to better understand vascular inflammation driving AAA formation and potential intervene medically.Professional Practice Gap There is a lack of proven medical therapy to prevent AAA growth. This abstract demonstrates that macrophage epigenetic modifications regulate inflammation in AAAs and highlights a new mechanism to target. 
The Perfuse Dual Chamber Stent Improves Donor Organ Recovery In A Porcine Model
  • Basic and Translational Research
  • Bio Medical Engineering Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge Strategy Use of a dual chamber stent to improve organ recovery and reduce ischemic injury.Professional Practice Gap Perfusion of abdominal organs during organ recovery.
Endovascular Repair Of Blunt Thoracic Aortic Trauma Is Associated With Increased Left Ventricular Mass, Hypertension, And Off-target Aortic Remodeling
  • Basic and Translational Research
  • Aortic Aneurysm Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge StrategyTrauma TEVAR is associated with LV mass increase, development of hypertension, and off-target accelerated expansile ascending aortic remodeling. Our findings call for better follow-up of young patients receiving stent-grafts and for improved endovascular devices capable of preserving optimal ventricular-arterial coupling.
Maresin 1 Attenuates Murine Abdominal Aortic Aneurysms Via Vascular Smooth Muscle Cell Dependent TGF-β Signaling
  • Basic and Translational Research
  • Aortic Aneurysm Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge StrategyThere currently exists no successful medical management of abdominal aortic aneurysms. This research helps to identify potential therapeutic targets and mechanisms in the treatment of this disease.Professional Practice GapThis research addresses potential medical therapies in the treatment of AAA as currently operative intervention remains the only definitive treatment.
A Theranostic Role For Ccr2 In Rodent Abdominal Aortic Aneurysm Development And Rupture
  • Basic and Translational Research
  • Translational Science Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge Strategy Develop new diagnostic and treatment modalities for AAAProfessional Practice Gap Experimental AAA models are subacute.
Pharmacological Inhibition Of Bruton's Tyrosine Kinase Attenuates Experimental Abdominal Aortic Aneurysms
  • Basic and Translational Research
  • Translational Science Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices.Knowledge StrategyThis study demonstrated that BTK inhibitor ibrutinib, FDA-approved drug, attenuated the formation of, and further progression of established, experimental AAAs in two mechanistically distinct but complementary AAA model systems. Our results suggest that pharmacological inhibition of BTK may represent a novel translational strategy for AAA disease suppression.
Landscape Of Human Secretome In Abdominal Aortic Aneurysm Profiled By Single-cell RNA Sequencing
  • Basic and Translational Research
  • Aortic Aneurysm Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. 
Autophagy Remodels Mitochondria During Differentiation And Enhances Longevity Through Ulk1 Kinase Signaling Of Induced Pluripotent Stem Cell-derived Endothelial Cells
  • Basic and Translational Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 4: Vascular Regeneration, Stem Cells, and Wound Healing.
Downregulation Of Inflammation And A Cascade Of Pro-angiogenic Signals Mediate The Beneficial Effects Of Gene-modified Stem Cell Therapy In Hindlimb Ischemia
  • Basic and Translational Research
  • Ischemia
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 4: Vascular Regeneration, Stem Cells, and Wound Healing. Knowledge StrategyWe attempt to increase stem cell's inherent therapeutic potential with a novel vector to increase cell's homing capabilities and overall potency.

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