Title
Category
Credits
Event date
Cost
Periadventitial Delivery of Simvastatin From Microparticles Attenuates Arteriovenous Fistula Outflow Vein Neointimal Hyperplasia
  • Basic and Translational Research
  • Neo Intimal Hyperplasia
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 1: Arterial Remodeling and Discovery Science for Venous Disease. Knowledge StrategyPeriadventitial delivery of simvastatin from microparticles attenuates arteriovenous fistula outflow vein neointimal hyperplasia. It provides a new option to prevent arteriovenous fistula failure.Professional Practice GapIn the present study, there was no assembled marker on simvastatin or microparticles, which could illustrate migration or residual dose in the outflow veins. 
Absence Of Cpla2 In Lrp1 Smooth Muscle Cell Deficient Mice Promotes Severe Aortic Atherosclerotic Disease
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System Knowledge StrategyResults from our studies will identify molecular mechanisms in the process of underpinning novel therapeutic targets for the devastating consequences of treating atherosclerotic disease plaque vulnerability and rupture by studying bioactive lipid dysregulation.
Serum Circulating Fatty Acid Synthase As A Diagnostic Biomarker For Chronic Limb-Threatening Ischemia
  • Basic and Translational Research
  • Extremity Ischemia
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System.Knowledge StrategyThis study showed that circulating fatty acid synthase (cFAS) is independently associated with CLTI but not DM. Future studies may explore using cFAS as biomarker for severity of PAD to guide clinical management, or as a target for development of medical therapeutics.
ZEB2 Regulates Activation And Exhaustion Programming Of CD8+ T Cells In Atherosclerosis
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System. 
The Role Of Mast Cells In Atherosclerotic Plaque Calcification
  • Basic and Translational Research
  • Atherosclerosis Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System.Knowledge StrategyMast cell phenotype and secreting mediators could be detected in the plasma of patients with carotid atherosclerotic plaque and predict the clinical outcome of the patient.
Polygenic Risk Score Identifies Patients At Increased Risk For Abdominal Aortic Aneurysm And May Benefit From Ultrasound Screening
  • Basic and Translational Research
  • Aortic Aneurysm Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 2: Atherosclerotic Disease and Role of the Immune System. Knowledge StrategyThrough the use of low cost genotyping, we are able to identify a subset of the population at higher risk for AAA and who may benefit from screening beyond the current USPSTF recommendations.
Epigenetic Modifications Influence Macrophage-mediated Inflammation Inabdominal Aortic Aneurysms
  • Basic and Translational Research
  • Epigenetics in Vascular Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge Strategy The results of this study allow us to better understand vascular inflammation driving AAA formation and potential intervene medically.Professional Practice Gap There is a lack of proven medical therapy to prevent AAA growth. This abstract demonstrates that macrophage epigenetic modifications regulate inflammation in AAAs and highlights a new mechanism to target. 
The Perfuse Dual Chamber Stent Improves Donor Organ Recovery In A Porcine Model
  • Basic and Translational Research
  • Bio Medical Engineering Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge Strategy Use of a dual chamber stent to improve organ recovery and reduce ischemic injury.Professional Practice Gap Perfusion of abdominal organs during organ recovery.
Endovascular Repair Of Blunt Thoracic Aortic Trauma Is Associated With Increased Left Ventricular Mass, Hypertension, And Off-target Aortic Remodeling
  • Basic and Translational Research
  • Aortic Aneurysm Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge StrategyTrauma TEVAR is associated with LV mass increase, development of hypertension, and off-target accelerated expansile ascending aortic remodeling. Our findings call for better follow-up of young patients receiving stent-grafts and for improved endovascular devices capable of preserving optimal ventricular-arterial coupling.
Maresin 1 Attenuates Murine Abdominal Aortic Aneurysms Via Vascular Smooth Muscle Cell Dependent TGF-β Signaling
  • Basic and Translational Research
  • Aortic Aneurysm Research
$0.00
This activity was presented at 2020 VRIC as part of Abstract Session 3: Aortopathies and Novel Vascular Devices. Knowledge StrategyThere currently exists no successful medical management of abdominal aortic aneurysms. This research helps to identify potential therapeutic targets and mechanisms in the treatment of this disease.Professional Practice GapThis research addresses potential medical therapies in the treatment of AAA as currently operative intervention remains the only definitive treatment.

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